![]() ![]() Excretion: Some nonsteroidal antiinflammatory drugs ( NSAIDs), like indomethacin, may lower kidney function and affect the excretion of lithium, a drug used for bipolar disorder.High blood levels of simvastatin can lead to serious liver and muscle side effects. Diltiazem can inhibit (block) the CYP450 3A4 enzymes needed for the breakdown (metabolism) of simvastatin. For example, using diltiazem (a blood pressure medication) with simvastatin (a medicine to lower cholesterol) may elevate the blood levels and side effects of simvastatin. However, enzyme levels may go up or down and affect how drugs are broken down. ![]() Enzymes in the liver, usually the CYP450 enzymes, are often responsible for breaking down drugs for elimination from the body. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |